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This Week in Psychiatry – 1/31/11

January 28, 2011

Full Recovery from BDD Often Likely, Study Finds

A recent report in The Journal of Nervous and Mental Disease addressed the course of illnessof body dysmorphic disorder (BDD). Of 514 subjects in the Harvard/Brown Anxiety Research Project, 17 (3.3%) had current BDD and 22 (4.3%) had lifetime BDD at study outset. Over the 8-year study period, the probability of full recovery from BDD, and probability of recurrence once remitted, was 0.76 and 0.14, respectively.

Can Fluoxetine Improve Recovery For Some Types of Stroke-Induced Paralysis?

Fluoxetine may improve physiological recovery following ischemic stroke, according to a Lancet Neurology report. The double-blind randomized controlled trial included patients with ischemic stroke with hemiplegia or hemiparesis, and a Fugl-Meyer motor scale (FMMS) score of ≤55. Subjects were prescribed fluoxetine 20 mg/day for 3 months 5–10 days following stroke (treatment group, n=57; placebo group, n=56). All subjects received physiotherapy. The treatment group demonstrated significantly greater improvement in the primary outcome measure, FMMS score at 90 days (34 points [95% CI, 29.7–38.4]), compared to placebo (24.3 points [19.9–28.7]; P=.003). The authors suggest that manipulating brain plasticity may account for the treatment group’s improvement

“This Week in Psychiatry” is written by Lonnie Stoltzfoos

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